Endocrine Abstracts

Hyperglycaemic hyperosmolar state (HHS) is a common medical presentation, typically occurring in older patients with Type 2 diabetes mellitus. Mortality rates have been reported to be up to 60%. Precipitating factors include dehydration, sepsis, cardiovascular disease and drugs. Here, we describe a rare case of HHS, likely to have been precipitated following the development of lithium-induced nephrogenic diabetes insipidus (DI).A 62-year-old female prese...

Case history: We describe a rare case of a 59-year-old woman, whose hypercortisolism was unmasked following transphenoidal surgery for Acromegaly. She presented to the Endocrine Clinic in 2006 with acromegalic features and MRI revealing a pituitary macroadenoma 20×18×18 mm. Repeat dynamic evaluation showed inadequate GH suppression (initially normal), raising the possibility of early rumbling Acromegaly. 0900 h serum cortisol was 287 nmol/l. She was started on Caberg...

Coexistence of Acromegaly with Cushing’s syndrome in the same individual is rare. We herein describe a case of a 59-year-old woman, whose hypercortisolism was unmasked following transphenoidal surgery for Acromegaly.She presented to the Endocrine Clinic in 2006 with acromegalic features and MRI revealing a pituitary macroadenoma 20×18×18 mm. Repeat dynamic evaluation showed inadequate GH suppression (initially normal), raising the possibil...